Area A

Pathogen recognition in the lung and initiation of innate immune response

Area B

Humoral and cell-based bronchoalveolar defence mechanisms

Area C

Control of host response in the bronchoalveolar compartment and strategies for intervention

A1 – Bauer / Opitz

Role of innate immune receptors in preventing hyper-inflammation and promoting repair during bacterial pneumonia

B1 – Zahlten / Suttorp / Hain

Peptidoglycan recognition proteins (PGLYRPs) as regulators of innate immunity in the lung

C1 – Schmeck/ Vingron

MicroRNA in the pathogenesis of Legionella pneumonia

A2 – Wygrecka / Preissner

The role of enolase-1 and extracellular nucleic acids in lung infection and their contribution to innate immune responses and bacterial tropism

B2 – Herold / Pleschka / Wolff

Novel pathways of alveolar epithelial cell injury in influenza virus pneumonia: cellular cross-talks and virus-host interactions

C3 – Mayer / Witzenrath

Resolvin E1 and related lipid mediators programming the resolution of inflammation in pneumonia

A4 – Pillich / Chakraborty

Pathophysiological roles of endoplasmic reticulum stress, autophagy and microvillus inclusion during infection with Streptococcus pneumoniae

B3 – Hackstein / Bauer / Lohmeyer

Development and function of respiratory macrophages and dendritic cell subsets during bacterial pneumonia

C6 – Witzenrath / Weissmann

The Angiopoietin-/Tie-2 system in severe pneumonia

A5 – Opitz / Chaput / Heimesaat

Cross-talk of antimicrobial therapy, microbiota and innate immunity in pneumonia caused by multidrug-resistant Gram-negative bacteria

B5 – Meisel A / Meisel C

Paralysis of pulmonary immunity after cerebral ischemia by parasympathetic nervous system

C7 – Fischer / Müller-Redetzky

Host extracellular nucleic acids in severe pneumonia: Mechanisms and therapeutic approaches with adrenomedullin

A6 – Krasteva-Christ / Kummer

Pathogen recognition by taste receptors and coupling to mucociliary clearance

B6 – Hocke / Hippenstiel

Role of mitochondria for innate immune activation in pneumonia

C8 – Seeberger / Sander

Tuning innate immune responses to augment anti-carbohydrate vaccines against bacterial pneumonia

Area Z: Service Projekte

Z1a – Hocke

“High-end” microscopy in cellular microbiology of the lung

Z1b – Gruber

Experimental histopathology, advanced histomorphometrical digital image analysis, molecular pathology and tissue banking

Moduls

T1 – Hocke / Hippenstiel / Hassel

High-pressure water jet cutting for long-term intravital microscopy based analysis of innate immune mechanisms of human lung

EN1 – Sander

Regulation of protective pulmonary immunity by innate pathways sensing bacterial viability