Transregio SFB-TR 84 “Innate Immunity of the Lung: Mechanisms of Pathogen Attack and Host Defence in Pneumonia“



Experimental histopathology, advanced histomorphometrical digital image analysis, molecular pathology and tissue banking (Gruber / Trimpert)


All projects within the SFB-TR 84 will perform infection studies using in vivo mouse models or ex vivo human lung samples to test their hypotheses, mostly targeting individual molecules, pathways, or therapies. The pathology Z-project will provide a wide spectrum of pathology analytic services to place their experimental data into a wider context of the entire lungs and the whole organisms.

We will provide all classical and novel molecular pathology methodologies, including our developments of highly innovative digital image analysis tools. Our tissue bank will archive all experimental samples and offer them for double and multiple uses which will allow to drastically reduce the number of required experimental animals.