Transregio SFB-TR 84 “Innate Immunity of the Lung: Mechanisms of Pathogen Attack and Host Defence in Pneumonia“

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Publications

Jagdmann S, Berchtold D, Gutbier B, Witzenrath M, Meisel A, Meisel C, Dames C

Efficacy and safety of intratracheal IFN-γ treatment to reverse stroke-induced susceptibility to pulmonary bacterial infections

J Neuroimmunol. 2021 Jun 15;355:577568. doi: 10.1016/j.jneuroim.2021.577568. Epub 2021 Apr 3. PMID: 33862420. pubmed.ncbi.nlm.nih.gov/33862420/

Weitbrecht L, Berchtold D, Zhang T, Jagdmann S, Dames C, Winek K, Meisel C, Meisel A.

CD4 + T cells promote delayed B cell responses in the ischemic brain after experimental stroke

Brain Behav Immun. 2021 Jan;91:601-614. doi: 10.1016/j.bbi.2020.09.029. Epub 2020 Sep 28. https://pubmed.ncbi.nlm.nih.gov/33002634/

Winek K, Lobentanzer S, Nadorp B, Dubnov S, Dames C, Jagdmann S, Moshitzky G, Hotter B, Meisel C, Greenberg DS, Shifman S, Klein J, Shenhar-Tsarfaty S, Meisel A, Soreq H.

Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade

Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32606-32616. doi: 10.1073/pnas.2013542117. Epub 2020 Dec 7. https://pubmed.ncbi.nlm.nih.gov/33288717/

Jagdmann S, Dames C, Berchtold D, Winek K, Weitbrecht L, Meisel A, Meisel C.

Impact of Key Nicotinic AChR Subunits on Post-Stroke Pneumococcal Pneumonia

Vaccines (Basel). 2020 May 28;8(2):253. doi: 10.3390/vaccines8020253. https://pubmed.ncbi.nlm.nih.gov/32481512/

Hotter B, Hoffmann S, Ulm L, Montaner J, Bustamante A, Meisel C, Meisel A.

Inflammatory and stress markers predicting pneumonia, outcome, and etiology in patients with stroke: Biomarkers for predicting pneumonia, functional outcome, and death after stroke

Neurol Neuroimmunol Neuroinflamm. 2020 Feb 25;7(3):e692. doi: 10.1212/NXI.0000000000000692. Print 2020 May. https://pubmed.ncbi.nlm.nih.gov/32098866/

Oyama N, Winek K, Bäcker-Koduah P, Zhang T, Dames C, Werich M, Kershaw O, Meisel C, Meisel A, Dirnagl U.

Exploratory Investigation of Intestinal Function and Bacterial Translocation After Focal Cerebral Ischemia in the Mouse

Front Neurol. 2018 Nov 19;9:937. doi: 10.3389/fneur.2018.00937. eCollection 2018. https://pubmed.ncbi.nlm.nih.gov/30510535/

Dames C, Winek K, Beckers Y, Engel O, Meisel M, Meisel C

Immunomodulatory treatment with systemic GM-CSF augments pulmonary immune responses and improves neurological outcome after experimental stroke.

J Neuroimmunol. 2018 Mar 9. pii: S0165-5728(17)30548-9

http://www.jni-journal.com/article/S0165-5728(17)30548-9/fulltext

Ulm L, Hoffmann S, Nabavi D, Hermans M, Mackert BM, Hamilton F, Schmehl I, Jungehuelsing GJ, Montaner J, Bustamante A, Katan M, Hartmann A, Ebmeyer S, Dinter C, Wiemer JC, Hertel S, Meisel C, Anker SD, Meisel A.

The Randomized Controlled STRAWINSKI Trial: Procalcitonin-Guided Antibiotic Therapy after Stroke

Front Neurol. 2017 Apr 24;8:153. doi: 10.3389/fneur.2017.00153. eCollection 2017. https://pubmed.ncbi.nlm.nih.gov/28484421/

Winek K, Engel O, Koduah P, Heimesaat MM, Fischer A, Bereswill S, Dames C, Kershaw O, Gruber AD, Curato C, Oyama N, Meisel C, Meisel A, Dirnagl U

Depletion of cultivatable gut microbiota by broad-spectrum antibiotic pretreatment worsens outcome after murine stroke.

Stroke. 2016 May;47(5):1354-63

https://www.ncbi.nlm.nih.gov/pubmed/27056982

Engel O, Akyüz L, da Costa Goncalves AC, Winek K, Dames C, Thielke M, Herold S, Böttcher C, Priller J, Volk HD, Dirnagl U, Meisel C, Meisel A

Cholinergic pathway suppresses pulmonary innate immunity facilitating pneumonia after stroke.

Stroke. 2015 Nov;46(11):3232-40

http://www.ncbi.nlm.nih.gov/pubmed/26451017

Dames C, Akyüz L, Reppe K, Tabeling C, Dietert K, Kershaw O, Gruber AD, Meisel C, Meisel A, Witzenrath M, Engel O

Miniaturized bronchoscopy enables unilateral investigation, application, and sampling in mice.

Am J Respir Cell Mol Biol. 2014 Dec;51(6):730-7

http://www.ncbi.nlm.nih.gov/pubmed/24960575

Hetze S, Engel O, Römer C, Mueller S, Dirnagl U, Meisel C, Meisel A.

Superiority of preventive antibiotic treatment compared with standard treatment of poststroke pneumonia in experimental stroke: a bed to bench approach

J Cereb Blood Flow Metab. 2013 Jan 30. doi: 10.1038/jcbfm.2013.6. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/23361393